WebFeb 1, 2007 · Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation - ScienceDirect Abstract Introduction Section snippets … The oxysterol-binding protein (OSBP)-related proteins (ORPs) are a family of lipid transfer proteins (LTPs). Concretely, they constitute a family of sterol and phosphoinositide binding and transfer proteins in eukaryotes that are conserved from yeast to humans. They are lipid-binding proteins implicated in … See more All oxysterol related proteins (ORP) contain a core lipid-binding domain (ORD), which has a characteristic amino acids sequence, EQVSHHPP. The most studied ORP are human and yeast ones, and the only OSBP-ORP … See more Some oxysterols have been found to contribute to the inflammation and oxidative damage as well as in cell death in the appearance and especially the development of … See more As part of the Lipid Transfer proteins (LTPs) family, ORPs have different and variate functions. This functions include signaling, vesicular trafficking, lipid metabolism and … See more
B IBLIOGRAPHY - by the human oxysterol-binding protein (OSBP)
WebFeb 5, 2024 · Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function. Ngo M, et al. Mol Biol Cell, 2009 Mar. PMID 19129476, Free PMC Article OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface. Zhou Y, et al. Exp Cell Res, 2010 Nov 15. WebAug 20, 2010 · 606737 - OXYSTEROL-BINDING PROTEIN-LIKE PROTEIN 9; OSBPL9 - OSBP-RELATED PROTEIN 9; ORP9 - OSBPL9 Toggle navigation ... N. D. VAMP-associated … balbriggan dublin ireland
Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 …
WebApr 10, 2024 · Using a multiscale simulation approach tailored to studying lipid transport, we elucidate key steps in the molecular mechanism used by CPTP to rapidly transport C1P between membranes: Through conformational changes that are coupled to membrane binding, CPTP significantly disrupts C1P’s local hydrophobic environment in a membrane … WebThe binding results suggest multiple modes of steroidal ligand binding to OSBP and ORP4, and a library of 20(S)-hydroxycholesterol analogues with varying sterol side chains reveal that side chain length modifications are not well tolerated for OSBP-related protein 4 interactions. Oxysterol-binding protein (OSBP) and OSBP-related protein 4 (ORP4) have … WebApr 13, 2024 · Oxysterol-binding protein (OSBP)-related proteins (ORPs), including OSBP homologs (Osh1–Osh7) of Saccharomyces cerevisiae, are candidates for lipid transfer … arif maftuhin uin sunan kalijaga